Fatigue mechanisms

Fundamental research on fatigue

[Selection]

*: represents trainees under my supervision, #: review article.

*Brownstein CG, Espeit L, *Royer N, Ansdell P, Škarabot J, Souron R, Lapole T, Millet GY. Reductions in motoneuron excitability during sustained isometric contractions are dependent on stimulus and contraction intensity. J Neurophysiol 125(5): 1636-1646, 2021 (IF: 2.7).

*Azevedo R, Forot J, Iannetta D, MacInnis MJ, Millet GY, Murias JM. Slight power output manipulations around the maximal lactate steady state have an impact on fatigue in females and males. J Appl Physiol 130(6): 1879-1892, 2021 (IF: 3.5)

Varesco G, *Royer N, *Singh B, *Parent A, Féasson L, Lapole T, Millet GY, Rozand V. Reliability and agreement of a dynamic quadriceps incremental test for the assessment of neuromuscular function. J Electromyogr Kinesiol 56:102503, 2021.

*Azevedo R, Milioni F, Murias JM, Bertuzzi R, Millet GY. Dynamic changes of performance fatigability and muscular O2 saturation during a 4-km cycling time trial. Med Sci Sports Exerc 53(3):613-623, 2021.

*Milioni F, *Azevedo RA, Zagatto AM, Millet GY. Time-course of recovery after repeated sprints in cycling. Med Sci Sports Exerc 53(2): 413–420, 2021.

Bertuzzi R, Silva-Cavalcante MD, Couto PG, *de Almeida Azevedo R, Coelho DB, Zagatto A, Lima-Silva AE, Millet GY. Prior upper body exercise impairs 4-km cycling time-trial performance without altering neuromuscular function. Res Q Exerc Sport 92(1): 52-62, 2021.

*Brownstein CG, Espeit L, *Royer N, Lapole T, Millet GY. Fatigue-induced change in short-interval intracortical inhibition and silent period duration using stimulus intensities evoking maximal versus submaximal responses. J Appl Physiol 129(2):205-217, 2020.

*Froyd C, Beltrami FG, Millet GY, MacIntosh BR, Noakes TD. Greater short-time recovery of peripheral fatigue after short compared with long duration time-trial. Front Physiol 11: 399, 2020.

*Oranchuk DJ, *Koral J, *Ribeiro da Mota G, *Twomey R, Millet GY. Does sustained knee extensors maximal voluntary contraction induce full ischemia? Appl Physiol Nutr Metab 45(7): 698-706, 2020.

*Vernillo G, *Temesi J, *Martin M, *Krüger R, Millet GYSpinal contribution to neuromuscular recovery differs between elbow-flexor and knee-extensor muscles after a maximal sustained fatiguing task. J Neurophysiol 124(3): 763-773, 2020.

*Aboodarda SJ, Iannetta D, *Emami N, *Varesco G, Murias JM, Millet GY. Pre-induced fatigue and concurrent muscle pain elicit distinct effects on exercise tolerance, neuromuscular performance, and corticospinal excitability of locomotor muscles. J Physiol 598 (2) : 285-302, 2020.

*Koral J, *Oranchuk DJ, *Wrightson J *Twomey R, Millet GY. Mechanisms of fatigue and recovery in unilateral versus bilateral maximal voluntary contractions. J Appl Physiol 128(4): 785-794, 2020 .

*Temesi J, *Vernillo G, *Martin M, *Krüger R, McNeil CJ, Millet GY. Sustained maximal voluntary contractions elicit different neurophysiological responses in upper- and lower-limb muscles in men. Neuroscience 422: 88-98, 2019.

*Souron R, Baudry S, Millet GY, Lapole T. Vibration-induced depression in spinal loop excitability revisited. J Physiol 597 (21) : 5179-5193, 2019.

*Aboodarda SJ, *Zhang XY, *Cline M and Millet GY. Exercise-induced fatigue in one leg does not impair the neuromuscular performance in the contralateral leg but improves the excitability of the ipsilateral corticospinal pathway. Brain Sci 9 : 250, 2019.

*Aboodarda SJ, *Fan S, *Coates K, Millet GY. The short-term recovery of corticomotor responses and central fatigue in elbow flexors. BMC Neuroscience 20 (1) : 9, 2019.

*Krüger R, *Aboodarda SJ, *James LB, Samozino P, Millet GY. Cycling Performed on an Innovative Ergometer at Different Intensities-Durations in Men: Neuromuscular Fatigue and Recovery Kinetics. Appl Physiol Nutr Metab 44 (12) : 1320-1328, 2019.

Krüger RL, Aboodarda SJ, Jaimes LM, MacIntosh BR, Samozino P, Millet GY. Fatigue and Recovery Measured with Dynamic Properties vs Isometric Force: Effects of Exercise Intensity J Exp Biol 222 : jeb197483, 2019.

*Vernillo G, *Temesi J, *Martin M, Millet GY. Do aerobic characteristics explain isometric exercise-induced neuromuscular fatigue and recovery in upper and lower limbs? J Sports Sci 37 (4) : 387-39, 2019.

*Mira J, *Aboodarda SJ, *Floreani M, *Jaswal R, *Moon SJ, *Amery K, Rupp T, Millet GY. Effects of endurance training on neuromuscular fatigue - Part I : strength loss and muscle fatigue. Eur J Appl Physiol 118 (11) : 2281-2293, 2018.

*Aboodarda SJ, *Mira J, *Floreani M, *Jaswal R, *Moon SJ, *Amery K, Rupp T, Millet GY. Effects of endurance training on neuromuscular fatigue - Part II : corticospinal excitability and voluntary activation. Eur J Appl Physiol 118(11) : 2295-2305, 2018.

*Vernillo G, *Temesi J, *Martin M, Millet GY. Mechanisms of Fatigue and Recovery in Upper vs. Lower Limbs in Men. Med Sci Sports Exerc 50 (2) : 334-343, 2018.

*Souron R, *Besson T, McNeil, CJ, Lapole T, Millet GY. An Acute Exposure to Muscle Vibration Decreases Knee Extensors Force Production and Modulates Associated Central Nervous System Excitability. Front Neurosci 11 : 519, 2017.

*Temesi J, *Mattioni Maturana F, *Peyrard A, *Piucco T, Murias JM, Millet GY. The relationship between oxygen uptake kinetics and neuromuscular fatigue in high-intensity cycling exercise. Eur J Appl Physiol 117 (5) : 969-978, 2017.

*Aboodarda SJ, Sambaher N, Millet GY, Behm DG. Knee extensors neuromuscular fatigue changes the corticospinal pathway excitability in biceps brachii muscle. Neuroscience 340 : 477-486, 2017.

*Froyd C, Beltrami FG, Millet GY, Noakes TD. No critical threshold in peripheral fatigue at task failure for isometric trials. Front Physiol 7 : 627, 2016.

*Arnal PJ, Lapole T, Erblang M, Guillard M, Bourrihlon C, Leger D, Chennaoui M, Millet GY. Sleep extension before sleep loss: effects on performance and neuromuscular function. Med Sci Sports Exerc, 48 (8) :1595-603, 2016. This article was chosen for an editorial comment in the same journal.

*Froyd C, Beltrami FG, Millet GY, Noakes TD. Central regulation and neuromuscular fatigue in exercise trials of different durations. Med Sci Sports Exerc 48 (6) : 1024-1032, 2016.

*Arnal PJ, Sauvet F, Leger D, Van Beers P, Bayon V, Bougard C, Rabat A, Millet GY, Chennaoui M. Benefits of Sleep Extension on Sustained Attention and Sleep Pressure Before and During Total Sleep Deprivation and Recovery. Sleep 38 (12) : 1935-1943, 2015. This article was chosen for an editorial comment.

*Rupp T, Mallouf TL, Perrey S, Wuyam B, Millet GY, Verges S. CO2 Clamping, Peripheral and Central Fatigue during Hypoxic Knee Extensions in Men. Med Sci Sports Exerc 47 (12) : 2513-2524, 2015.

Gruet M, *Temesi J, *Rupp T, Levy P, Vergès S, Millet GY. Dynamics of corticospinal changes during and after a high-intensity quadriceps exercise. Exp Physiol 99 (8) :1053-1064, 2014.

Hureau T, Olivier N, Millet GY, Meste O, Blain G. Exercise performance is regulated during repeated sprints to limit the development of peripheral fatigue beyond a critical threshold. Exp Physiol 99 (7) : 951-963, 2014.

*Froyd C, Millet GY, Noakes T.D. The development of peripheral fatigue and short-term recovery during self-paced high-intensity exercise. J Physiol 591 (Pt 5) : 1339-1346, 2013.

Decorte N, Lafaix PA, Millet GY, Wuyam B and Verges S. Central and peripheral fatigue kinetics during exhaustive constant-load cycling. Scand J Med Sci Sports 22 : 381-391, 2012.